Microscale Bioengineering
About
The Microscale Bioengineering Group has been successfully developing microfluidic tools for applied research in Industrial Biotechnology and fundamental research in microbiology since 2010. We are pioneers in the field. Our mission is to engineer bottom-up concepts for microbial single-cell analysis to tackle questions that cannot be answered by applying conventional systems at laboratory scale. In highly interdisciplinary projects, we exploit the potential of cultivations at the femto- to picoliter scale, revealing unseen insights into mixed cultures, population heterogeneity, cellular interactions, single-cell physiology and more. Fluids at micrometer scales behave differently, resulting in laminar flow and diffusion governed mass transport, enabling accurate micro environmental control. Recently we have been focusing on additional chip functionality creating artificial cultivation landscapes and mimicking structured environments and dynamics.
Research Topics
- SimBal – DFG (2020-2025), SPP 2170
- 1+1=1: Bioengineering synthetic symbiosis to illuminate how a microalga becomes an endosymbiont (HFSP 2025-2028)
- Advanced oxygen control – Jasso, Japanese Student Organisation
- High CO2 – Helmholtz Innovation Pool
- MibiNet - In vitro evolution of a synthetic organelle inside a picolitre habitat (A07)
