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Synthetic Cell Factories

Head of Department

Gruppenfoto SyncellAugust 2021

Prof. Dr. Jan Marienhagen
Institute of Bio- and Geosciences
IBG-1: Biotechnology
Forschungszentrum Jülich GmbH
52425 Jülich
Germany











We want to contribute to the understanding of bacterial metabolism and are interested in expanding the biosynthetic capabilities of microorganisms for applied purposes.

We focus on the engineering of Corynebacterium glutamicum for the sustainable production of value-added small molecules such as natural products, fine chemicals or pharmaceutical building blocks from biomass and other waste streams rich in carbon and energy.

In addition, we are developing new molecular tools for the editing of bacterial genomes and the high-throughput screening of metabolite producing bacteria at the single cell level using biosensors and fluorescence-activated cell sorting (FACS).



Former head of group

Dr. Lothar Eggeling


 

News and Highlights

September 2021Melanie Krinke joins the group for the practical work on her Doctoral thesis – Welcome!
August 2021Manuscript “Metabolic and process Engineering for microbial production of protocatechuate with Corynebacterium glutamicum” accepted by “Biotechnology and Bioengineering” and is online ahead of print: https://doi.org/10.1002/bit.27909
August 2021Manuscript “Development of a Biosensor Platform for Phenolic Compounds Using a Transition Ligand Strategy” published in “ACS Synthetic Biology” (https://doi.org/10.1021/acssynbio.1c00165)
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