The Helmholtz School for Data Science in Life, Earth and Energy (HDS-LEE) provides an interdisciplinary environment for educating the next generation of data scientists in close contact to domain-specific knowledge and research. All three domains – life & medical sciences, earth sciences, and energy systems/materials – are characterized by the experimental generation of huge heterogeneously structured data sets, which have to be evaluated in order to obtain a holistic understanding of very complex systems.