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Recruitment of subjects from the Heinz Nixdorf Recall Study

Subjects of 1000BRAINS are participants of the Heinz Nixdorf Recall Study, a population-based epidemiologic study on cardiovascular diseases. In this study, citizens of three cities (Bochum, Essen, Mühlheim) in the Ruhr area in West Germany are repeatedly examined since 2000.

The study sample encompasses 4,814 participants who are now 55 to 85 years of age. They fill in a questionnaire on their personal situation annually and are examined in the study centre in Essen every five years. The aim of these examinations is to reveal how different influencing factors – such as genetic predisposition, psychosocial surroundings, environment, or the “metabolic syndrome”, a combined dysfunction of blood pressure and fat metabolism – affect the occurrence and the course of cardiovascular diseases.