Institute of Bio- and Geosciences
Journals 2013
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology
Applied and environmental microbiology 79(19), 6006-6015 (2013) [10.1128/AEM.01634-13]
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IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria
BMC biology 11(1), 122 (2013) [10.1186/1741-7007-11-122]
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TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation
Organic letters 15, 452-455 (2013) [10.1021/ol3031186]
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13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis
Chemistry & biology 20, 1012-1021 (2013) [10.1016/j.chembiol.2013.06.012]
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Psymberin - biologische Eigenschaften und Ansätze zu Total- und Analogasynthesen
Angewandte Chemie 125(42), 11164 - 11190 (2013) [10.1002/ange.201301259]
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Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation
Nucleic acids research 41(12), 6360-6369 (2013) [10.1093/nar/gkt312]
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Effects of uncertainties in experimental conditions on the estimation of adsorption model parameters in preparative chromatography
Computers & chemical engineering 55, 148 - 157 (2013) [10.1016/j.compchemeng.2013.04.013]
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Enzyme - Selektivität nutzbar machen
GIT 2013(4), 252-254 (2013)
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Cloud MapReduce for Monte Carlo bootstrap applied to Metabolic Flux Analysis
Future generation computer systems 29(2), 582-590 (2013) [10.1016/j.future.2011.10.007]
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Advanced in vivo applications of blue light photoreceptors as alternative fluorescent proteins
Photochemical & photobiological sciences 12(7), 1125-1134 (2013) [10.1039/c3pp50040c]
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Omix - A Visualization Tool for Metabolic Networks with Highest Usability and Customizability in Focus
Chemie - Ingenieur - Technik 85(6), 849-862 (2013) [10.1002/cite.201200234]
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Leaving home ain't easy: protein export systems in Gram-positive bacteria
Research in microbiology 164(6), 664 - 674 (2013) [10.1016/j.resmic.2013.03.014]
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Synthesis of Highly-Substituted Enantiomerically Pure Allylboronic Esters and Investigation of Their Stereoselective Addition to Aldehydes
The journal of organic chemistry 78(22), 11549 - 11559 (2013) [10.1021/jo402130u]
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Crystal and solution studies reveal that the transcriptional regulator AcnR of Corynebacterium glutamicum is regulated by citrate:Mg2+ binding to a non-canonical pocket
The journal of biological chemistry 288, 15800-15812 (2013) [10.1074/jbc.M113.462440]
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Zonal rate model for axial and radial flow membrane chromatography. Part I: Knowledge transfer across operating conditions and scales
Biotechnology & bioengineering 110(4), 1129-1141 (2013) [10.1002/bit.24771]
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Computational fluid dynamic simulation of axial and radial flow membrane chromatography: Mechanisms of non-ideality and validation of the zonal rate model
Journal of chromatography / A 1305, 114 - 122 (2013) [10.1016/j.chroma.2013.07.004]
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Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments
Biotechnology & bioengineering 110(1), 220 - 228 (2013) [10.1002/bit.24616]
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Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation
Journal of visualized experiments 82, 50560 (2013) [10.3791/50560]
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Engineering stereoselectivity of ThDP-dependent enzymes
The FEBS journal 280(24), 6374–6394 (2013) [10.1111/febs.12496]
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Combined Fluxomics and Transcriptomics Analysis of Glucose Catabolism via a Partially Cyclic Pentose Phosphate Pathway in Gluconobacter oxydans 621H
Applied and environmental microbiology 79(7), 2336-2348 (2013) [10.1128/AEM.03414-12]
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Destabilized eYFP variants for dynamic gene expression studies in Corynebacterium glutamicum
Microbial biotechnology 6(2), 196–201 (2013) [10.1111/j.1751-7915.2012.00360.x]
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Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level
Applied and environmental microbiology 79(21), 6730 - 6736 (2013) [10.1128/AEM.01804-13]
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Reengineered carbonyl reductase for reducing methyl-substituted cyclohexanones
Protein engineering design and selection 26(4), 291 - 298 (2013) [10.1093/protein/gzt001]
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Complex Regulation of the Phosphoenolpyruvate Carboxykinase Gene pck and Characterization of Its GntR-Type Regulator IolR as a Repressor of myo-Inositol Utilization Genes in Corynebacterium glutamicum
Journal of bacteriology 195(18), 4283 - 4296 (2013) [10.1128/JB.00265-13]
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Conversion of Corynebacterium glutamicum from an aerobic respiring to an aerobic fermenting bacterium by inactivation of the respiratory chain
Biochimica et biophysica acta / Bioenergetics 1827(6), 699 - 708 (2013) [10.1016/j.bbabio.2013.02.004]
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Biochemical characterization of an alcohol dehydrogenase from Ralstonia sp.
Biotechnology & bioengineering 110(7), 1838 - 1848 (2013) [10.1002/bit.24857]
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Glycerol as a substrate for aerobic succinate production in minimal medium with Corynebacterium glutamicum
Microbial biotechnology 6(2), 189–195 (2013) [10.1111/j.1751-7915.2012.00347.x]
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Transkriptionsregulatoren im Dienste der Biotechnologie
Biospektrum 19(7), 739 - 741 (2013) [10.1007/s12268-013-0385-y]
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Metabolic engineering of microorganisms for the synthesis of plant natural products
Journal of biotechnology 163(2), 166 – 178 (2013) [10.1016/j.jbiotec.2012.06.001]
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Quantitative quenching evaluation and direct intracellular metabolite analysis in Penicillium chrysogenum
Analytical biochemistry 438(1), 47 - 52 (2013) [10.1016/j.ab.2013.03.021]
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Crude glycerol-based production of amino acids and putrescine by Corynebacterium glutamicum
Bioresource technology 145, 254 - 258 (2013) [10.1016/j.biortech.2013.02.053]
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C-C-bond formation using ThDP-dependent lyases
Current opinion in chemical biology 17(2), 261–270 (2013) [10.1016/j.cbpa.2013.02.017]
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Benzylic hydroxylation of aromatic compounds by P450 BM3
Green chemistry 15(9), 2408 - 2421 (2013) [10.1039/c3gc40838h]
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Monitoring of population dynamics of Corynebacterium glutamicum by multiparameter flow cytometry
Microbial biotechnology 6(2), 157–167 (2013) [10.1111/1751-7915.12018] special issue: "The Corynebacterium Cell Factory"
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Research on industrial biotechnology within the CLIB-Graduate Cluster—Part III
Journal of biotechnology 167(2), 73 - 74 (2013) [10.1016/j.jbiotec.2013.07.022]
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Synthesis of 8-Desmethoxy Psymberin: A Putative Biosynthetic Intermediate Towards the Marine Polyketide Psymberin
Chemistry 19(25), 8300 - 8308 (2013) [10.1002/chem.201203149]
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The Psymberin Story-A detailed overview of its biological properties and approaches towards total and analogue syntheses
Angewandte Chemie / International edition 52(42), 10960 - 10985 (2013) [10.1002/anie.201301259]
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A new multicopper oxidase from Gram-positive bacterium Rhodococcus erythropolis with activity modulating methionine rich tail
Protein expression and purification 89(1), 97 - 108 (2013) [10.1016/j.pep.2013.02.003]
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Revisiting the Enantioselective Sequence Patterns in Enoate Reductases
ChemCatChem 5(3), 711 - 713 (2013) [10.1002/cctc.201200668]
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Enantiomerically Pure Allylboronic Esters as Versatile Reagents in the Enantioselective Synthesis of Dihydro-α-pyrone-Containing Natural Products
Synthesis 45(08), 1106 - 1114 (2013) [10.1055/s-0032-1318440]
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A Mild PPTS-Catalyzed Acetalization of α,β-Unsaturated Aldehydes: The First Single-Step Protocol towards Benzylic Acetals
Synthesis 45(06), 729 - 733 (2013) [10.1055/s-0032-1318169]
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Jahresrückblick Organische Chemie: Naturstoff(total)synthese
Nachrichten aus der Chemie 61, 278-279 (2013)
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Toward biotechnological production of adipic acid and precursors from biorenewables
Research on Industrial Biotechnology within the CLIB-Graduate Cluster - Part III, Meeting location,
Journal of biotechnology 167(2), 75-84 (2013) [10.1016/j.jbiotec.2012.07.008]
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Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria
Micromachines 4(4), 357 - 369 (2013) [10.3390/mi4040357]
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Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes
Journal of microbiological methods 95(3), 470 - 476 (2013) [10.1016/j.mimet.2013.09.002]
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Fast and accurate parameter sensitivities for the general rate model of column liquid chromatography
Computers & chemical engineering 56, 46 - 57 (2013) [10.1016/j.compchemeng.2013.04.021]
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A Finite Element Method for Spatially Resolved Simulation of Packed Bed Chromatography
Proceedings in applied mathematics and mechanics 13(1), 511 - 512 (2013) [10.1002/pamm.201310248]
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Evidence for a Key Role of Cytochrome bo3 Oxidase in Respiratory Energy Metabolism of Gluconobacter oxydans
Journal of bacteriology 195(18), 4210 - 4220 (2013) [10.1128/JB.00470-13]
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Role of the pentose phosphate pathway and the Entner–Doudoroff pathway in glucose metabolism of Gluconobacter oxydans 621H
Applied microbiology and biotechnology 97(10), 4315-4323 (2013) [10.1007/s00253-013-4707-2]
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Secretory production of an FAD cofactor-containing cytosolic enzyme (sorbitol-xylitol oxidase from Streptomyces coelicolor ) using the twin-arginine translocation (Tat) pathway of Corynebacterium glutamicum
Microbial biotechnology 6(2), 202–206 (2013) [10.1111/1751-7915.12005]
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Simultaneous utilization of glucose and gluconate in Penicillium chrysogenum during overflow metabolism
Biotechnology & bioengineering 110(12), 3235 - 3243 (2013) [10.1002/bit.24974]
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Fusion of a Flavin-Based Fluorescent Protein to Hydroxynitrile Lyase from Arabidopsis thaliana Improves Enzyme Stability
Applied and environmental microbiology 79(15), 4727 - 4733 (2013) [10.1128/AEM.00795-13]
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Two Steps in One Pot: Enzyme Cascade for the Synthesis of Nor(pseudo)ephedrine from Inexpensive Starting Materials
Angewandte Chemie / International edition 52(26), 6772 - 6775 (2013) [10.1002/anie.201300718]
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Reductive whole-cell biotransformation with Corynebacterium glutamicum: improvement of NADPH generation from glucose by a cyclized pentose phosphate pathway using pfkA and gapA deletion mutants
Applied microbiology and biotechnology 97(1), 143 - 152 (2013) [10.1007/s00253-012-4314-7]
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Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water
Angewandte Chemie / International edition 52(8), 2359 - 2363 (2013) [10.1002/anie.201204464]
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Performance of iterative equation solvers for mass transfer Problems in three-dimensional sphere packings in COMSOL
Simulation modelling practice and theory 33, 115-131 (2013) [10.1016/j.simpat.2012.10.004]
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Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs
Proceedings of the National Academy of Sciences of the United States of America 110(5), 1827 - 1832 (2013) [10.1073/pnas.1220601110]
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Proline addition increases the efficiency of L-lysine production by Corynebacterium glutamicum
Engineering in life sciences 13(4), 393-398 (2013) [10.1002/elsc.201200187]
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Putting bugs to the blush: Metabolic engineering for phenylpropanoid-derived products in microorganisms
Bioengineered bugs 4(6), 1-8 (2013) [10.4161/bioe.23885]
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Genome-Wide Transcriptional Profiling of the Purple Sulfur Bacterium Allochromatium vinosum DSM 180T during Growth on Different Reduced Sulfur Compounds
Journal of bacteriology 195(18), 4231 - 4245 (2013) [10.1128/JB.00154-13]
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13CFLUX2--high-performance software suite for 13C-metabolic flux analysis
Bioinformatics 29(1), 143 - 145 (2013) [10.1093/bioinformatics/bts646]
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(S)-Selective MenD variants from Escherichia coli provide access to new functionalized chiral α-hydroxy ketones
Chemical communications 49, 2061-2063 (2013) [10.1039/c3cc38607d]
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Tailoring the S -Selectivity of 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate Synthase (MenD) from Escherichia coli
ChemCatChem 5, 3587 - 3594 (2013) [10.1002/cctc.201300318]
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Metabolic isotopomer labeling systems. Part III: Path tracing
Mathematical biosciences 244(1), 1-12 (2013) [10.1016/j.mbs.2013.02.012]
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Biotechnologie von morgen - DECHEMA-Fachgruppe "Systembiologie und Synthetische Biologie"
Biospektrum 06, 680-682 (2013)
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Isotopically non-stationary metabolic flux analysis: complex yet highly informative
Current opinion in biotechnology 24(6), 979 - 986 (2013) [10.1016/j.copbio.2013.03.024]
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Bio-based production of organic acids with Corynebacterium glutamicum
Microbial biotechnology 6(2), 87–102 (2013) [10.1111/1751-7915.12013]
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C1 Metabolism in Corynebacterium glutamicum: an Endogenous Pathway for Oxidation of Methanol to Carbon Dioxide
Applied and environmental microbiology 79(22), 6974 - 6983 (2013) [10.1128/AEM.02705-13]
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Dissertations 2013
Development of a biocatalytic production process for (S)-α-hydroxy ketones
90 p. (2013) = Heinrich-Heine-Universität Düsseldorf, Diss., 2013
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Rapid development of small-molecule producing microorganisms based on metabolite sensors
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich Reihe Gesundheit / Health 65, 141 p. (2013) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2012
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Regulatorische Aspekte der Expression und Sekretion heterologer Proteine in $\textit{Corynebacterium glutamicum}$
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Gesundheit / Health 62, 179 S. (2013) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2012
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Characterization of a novel phage-encoded actin-like protein and the function of the ChrSA two-component system in Corynebacterium glutamicum
114 p. (2013) = Heinrich-Heine-Universität Düsseldorf, Diss., 2013
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Stereoselective synthesis of vicinal diols with enzymatic cascade reactions
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Reihe Schlüsseltechnologien / Key Technologies 73, 177 p. (2013) = Universität Düsseldorf, Diss., 2013
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Metabolic engineering von $\textit{Corynebacterium glutamicum}$ für die Produktion einer Dicarbonsäure
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Gesundheit / Health 64, 98 S. (2013) = Heinrich-Heine-Universität Düsseldorf, Diss., 2012
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Modifikationen der Atmungskette in $\textit{Corynebacterium glutamicum}$ und Rolle des Flavohämoproteins Hmp
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Gesundheit / Health 68, IV, 119 S. (2013) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2013
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$\textit{Gluconobacter oxydans}$ strain development: Studies on central carbon metabolism and respiration
Jülich : Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Gesundheit / Health 63, III, 181 pp (2013) = Dissertation, Heinrich-Heine-Universität Düsseldorf, 2012
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Increasing the NADPH supply for whole-cell biotransformation and development of a novel biosensor
Jülich : Forschungszentrum Jülich GmbH, Zentralbibliothek, Verlag, Schriften des Forschungszentrums Jülich. Reihe Gesundheit / health 66, 127 S. (2013) = Heinrich-Heine-Universität Düsseldorf, Diss., 2013
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Targeted Quantification of Central Metabolic Enzymes in Corynebacterium glutamicum
104 p. (2013) = RWTH Aachen, Diss., 2013
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Finished master, bachelor and diploma thesis in 2013
Bachelor Thesis
Untersuchung des Exometaboloms von Corynebacterium glutamicum ATCC 13032 bei der Metabolisierung von Glucose, Acetat und Pyruvat
Essen 96 p. (2013) = Hochschule Niederrhein, Bachelorarbeit, 2013
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Bachelor Thesis
Untersuchung zur Klonierung und Charakterisierung technisch nutzbarer Enzyme aus Arabidopsis thaliana - Phenylalanin-Ammoniak-Lyase und Hydroxynitril-Lyase
80 p. (2013) = Johannes Gutenberg Universität Mainz, Bachelorarbeit, 2013
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Bachelor Thesis
Klonierung, Expression und Charakterisierung eines FRET-basierten Lysinsensors
82 p. (2013) = Heinrich-Heine-Universität Düsseldorf, Bachelorarbeit, 2013
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Master Thesis
Whole cell process strategies for modular synthetic Enzyme cascades towards diols
75 p. (2013) = RWTH Aachen, Masterarbeit, 2013
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Bachelor Thesis
Herstellung und Charakterisierung FRET-basierter Biosensoren
76 p. (2013) = RWTH Aachen, Bachelorarbeit, 2013
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Master Thesis
Ganzzelltransformation zur Synthese von (R)-2-Butanol in reinen Substratsystemen
88 p. (2013) = RWTH Aachen, Masterarbeit, 2013
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Master Thesis
Hochdurchsatz Evolution der Phosphoribosyltranserase in Corynebacterium glutamicum
100 pp. (2013) = RWTH Aachen, Masterarbeit, 2013
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Bachelor Thesis
Produktion von α-Ketoisocaproat mit Corynebacterium glutamicum
71 p. (2013) = Fachhochschule Aachen, Campus Jülich, Bachelorarbeit, 2013
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Master Thesis
Microbial Growth Studies in Well Controlled pL Environments on Single Cell Level
98 p. (2013) = RWTH Aachen, Masterarbeit, 2013
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Bachelor Thesis
Erweiterung der Toolbox Thiamindiphosphat-abhängiger Enzyme für die Synthese enantiokomplementärer a-Hydroxyketone: Charakterisierung von MenD aus Bacillus subtilis
101 p. (2013) = FH Aachen, Campus Jülich, Bachelorarbeit, 2013
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Master Thesis
The twin-arginine translocation (Tat) pathway: Investigation of substrate-translocase interactions during Tat-dependent protein translocation in E. coli.
76 p. (2013) = Brandenburgische Technische Universität Cottbus-Senftenberg, Masterarbeit, 2013
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Master Thesis
Expression und Analyse von Enzymen für die mikrobielle Produktion von Adipinsäure durch reverse β-Oxidation
90 p. (2013) = Fachhochschule Aachen, Campus Jülich, Masterarbeit, 2013
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Master Thesis
Entwicklung von Werkzeugen zur Überexpression von Genen in Corynebacterium
82 p. (2013) = Universität Rostock, Masterarbeit, 2013
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Bachelor Thesis
Intergenische Regionen für die genomische Integration heterologer Gene in Corynebacterium glutamicum - Plasmid-freie Produktion von Homocitrat
85 p. (2013) = Fachhochschule Aachen, Campus Jülich, Bachelorarbeit, 2013
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Diploma Thesis
Untersuchung einer neuartigen Technologie zur Probenpräparation für die Metabolomanalyse
104 p. (2013) = Technische Universität Dresden, Diplomarbeit, 2013
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Master Thesis
Markov Chain Monte Carlo Methods for Bayesian Inference and Viable Flux Volume Estimation of 13C Metabolic Network Models
168 p. (2013) = Universität Siegen, Masterarbeit, 2013
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Master Thesis
Analyse des Glycogenstoffwechsels in Corynebacterium glutamicum mittels isotopisch- instationärer 13C-Stoffflussanalyse
119 p. (2013) = RWTH Aachen, Masterarbeit, 2013
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Master Thesis
Untersuchungen zur Induktion und Infektiosität des CGP3 Prophagen in Corynebacterium glutamicum
62 p. (2013) = Heinrich-Heine-Universität Düsseldorf, Masterarbeit, 2013
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Master Thesis
Characterisation of the Energy Balance in Corynebacterium glutamicum
103 p. (2013) = Hochschule Lausitz, Masterarbeit, 2013
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Master Thesis
Untersuchung der Bedeutung des Exometaboloms für die Systembiologie
81 p. (2013) = FH Aachen, Campus Jülich, Masterarbeit, 2013
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Master Thesis
Hybrid Bioprocess Modelling of an Industrially Relevant Pharmaceutical Production Process: Parameterisation, Sensitivity, and Robustness Analysis with Modelica
118 p. (2013) = RWTH Aachen, Masterarbeit, 2013
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Bachelor Thesis
Realisierung einer Webservice-basierten Remote Computing Lösung für den High-Performance Simulator 13CFLUX2
39 p. (2013) = FH Aachen, Campus Jülich, Bachelorarbeit, 2013
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Diploma Thesis
Monte-Carlo-Vergleich von Versuchsplanungs-Algorithmen für die Bioprozessoptimierung
93 p. (2013) = Universität Siegen, Diplomarbeit, 2013
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