Cover Image - HMB Volume 43, Issue 11

We are pleased to announce that an illustration designed by INM-4, depicting the team's groundbreaking research in laminar fMRI of the brain, has been selected as the cover image for the August issue of Human Brain Mapping from among many cover submissions.

Cover Image - HMB Volume 43, Issue 11
Mapping of whole-cerebrum resting-state networks with the half-millimetre in-plane voxel enabling the identification of cortical depth-dependent activation.

HBM - Volume 43, Issue 11 August 1, 2022

The image relates to research conducted by INM-4 scientists who have successfully developed a novel fMRI technique that combines echo-planar-imaging with keyhole (EPIK) with repetition-time-external (TR-external) EPI phase correction to provide a half-millimetre in-plane spatial resolution (0.51 × 0.51 × 1.00 mm3 (0.26 mm3 voxel)) with whole-cerebrum coverage for the first time.

The work, published in the August edition of Human Brain Mapping, shows that the half-millimetre protocol can be used to detect activation profiles within the cortical regions and enables the identification of various resting-state networks distributed throughout the brain within a single fMRI session. The high-resolution functional images obtained further revealed mesoscale anatomical structures, such as small cerebral vessels and the internal granular layer of the cortex within the postcentral gyrus.

This development in imaging resting-state networks is anticipated to be particularly useful for investigating various neurological issues (e.g., cognitive dysfunction, psychiatric disorders, consciousness, etc.) with higher spatial precision than before. The method can also be applied to imaging young children (e.g., neonates, infants, etc.), where a fast acquisition is usually required.

Established in 1993, Human Brain Mapping is a peer-reviewed open access journal that aims to to develop the rapidly expanding field of human brain mapping by focussing on research derived using non-invasive brain imaging modalities to explore the spatial and temporal organisation of the neural systems supporting human behaviour.

Last Modified: 27.07.2022