Navigation and service

Picture of Miriam Menzel

Dr. rer. nat. Miriam Menzel

Postdoctoral Researcher

Academic degree: Ph.D. in Physics, RWTH Aachen University

Research Group Fiber Architecture, responsible for Scattering-Based Imaging

Klaus Tschira Boost Fellow

Research Topics

My research aims at developing new light microscopy techniques and analysis tools for brain research. In particular, I exploit the scattering of light to visualize nerve fibers and other brain tissue structures (Scattered Light Imaging, Scatterometry, Diattenuation Imaging). I am supervising multiple projects (Scattering-Based Imaging):

  • Development of scatterometry measurements with Scattered Light Imaging (SLI) for an improved evaluation of (crossing) nerve fiber orientations in brain tissue
  • Distinction between brain tissue types using SLI measurements with different wavelengths
  • Development of a high-speed SLI measurement protocol using compressed sensing
  • Design and development of a Scattering Polarimeter (combining SLI with polarization microscopy) for multi-modal measurements of brain tissue
  • Automated interpretation and visualization of SLI measurement results (software SLIX)
  • Enhanced interpretation of polarization microscopy measurements (3D-PLI) and automated segmentation of tissue types using multi-modal image analysis

Methods and Tools

  • Theoretical and experimental optics, polarimetry and scatterometry
  • Design and engineering of optical imaging systems
  • Automated, multi-modal image analysis and interpretation
  • Design of fault-tolerant imaging procedures
  • Computational imaging
  • Simulation and modeling of light-matter interactions (computational electrodynamics)
  • High performance computing

Address

Institute of Neuroscience and Medicine (INM-1)
Forschungszentrum Jülich
52425 Jülich

Contact

Phone: +49 2461 61-96359
Fax: +49 2461 61-3483
email: m.menzel@fz-juelich.de