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Inno4Vac: Innovations to accelerate vaccine development and manufacture

Vaccines are a huge public health achievement, saving an estimated 2.5 million lives every year and protecting millions more from illness and disability. However, developing new vaccines is extremely time consuming, costly and risky; on average it takes over 10 years and costs more than EUR 800 million to bring a vaccine to the market.

The aim of the Inno4Vac (https://cordis.europa.eu/project/id/101007799) project is to harness these advances and incorporate them into the vaccine industry. The project brings together experts in clinical research, immunology, microbiology, systems biology, mathematical models, and regulatory issues.

In this diverse team, the Institute of Bio- and Geosciences 1 (IBG-1) of Forschungszentrum Jülich (FZJ) will contribute computer-based tools for developing a modular computational platform for modelling the manufacture of vaccines. The CADET (https://cadet.github.io)  software, developed and maintained under supervision of Dr. Eric von Lieres (www.fz-juelich.de/ibg/ibg-1/lieres), will be applied for process simulation.

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The project is funded with 18.6 M€ by the European Union (EU) in the Innovative Medicines Initiative (IMI) program. The consortium comprises 12 pharmaceutical companies and small and medium enterprises (SME), and 29 universities and non-profit organizations.